We have a battery of tests planned at regular intervals including DNA methylation analysis, gene expression profile changes, telomere length (both TAT and QTRAP measured) and various other metrics that will highlight positive changes to aging biomarkers.
Gene therapy technology is much like computing technology. We had to build the super computer which cost $8 million in 1960. Now everyone has technologies that work predictably and at a cost the average person can afford.
Aging is one of the most visual diseases on the planet and includes things that we all know like wrinkles and grey hair, but also brain atrophy, muscle wasting and organ damage.
Work by Maria Blasco, Calvin Harley, Michael Fossel, Woodring Wright and Shay and Ronald Depinho in particular are of interest but there are literally thousands of articles relating to telomerase, telomeres and the biology behind it.
We can not control the aging reversal to a specific year today, that will come in the future. It is hypothesized that you will not reverse in physical appearance to less than a young adult. We see this in mice as well.
The gene therapies on my body are to measure the effects on humans. There is plenty of animal research to support these gene therapies but no one was conducting human tests.
I agree Maria Blasco has achieved amazing things with telomerase induction and we are hopeful this will translate to the human model.
BioViva is trying to help improve human health and wellbeing, and alleviate suffering. We are not trying to determine who should live or die. Everyone has a right to life without suffering.
Currently, we are working to deliver our anti-aging gene therapies to terminally ill people for compassionate care. Although, in the future we think that preventative medicine against aging would begin at a much younger age.
I have aging as a disease.
Our science and advisory board think that nuclear lamin dysfunction is a side-effect of DNA damage and mutations, rather than the cause. We are currently trying to mend nuclear dysfunction using Human Telomerase reverse transcriptase.